Writing PICOT Nursing Questions Writing PICOT Nursing Questions. A good clinical question has five principal elements. These elements include Patient/Problem, Intervention, Comparison, Outcome, and Time/Type of Question/Type of Study. In the absence of an accurately developed clinical question, researching relevant evidence can become difficult and overly time-consuming. PICOT, also known as PICO, is a specialized … Continue reading Writing PICOT Nursing Questions